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Home / Menopause & HRT / Estriol Vaginal Gel
Vaginal gel

Estriol Vaginal GelRx

estriol · vaginal gel, 1 g nightly

A physician-prescribed vaginal estriol gel that treats menopausal symptoms locally — vaginal dryness, irritation and discomfort with intimacy. Estriol is a milder estrogen often chosen for local relief, inserted at bedtime. Prescribed by a licensed U.S. provider and delivered to your door.

  • Relieves vaginal dryness, irritation and discomfort
  • Estriol — a milder estrogen, applied locally
  • Physician-prescribed — no insurance required
Choose your plan
$109/ month
Billed monthly · cancel anytime
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Only pay if you're prescribed
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No membership fee · same price at every dose

From the Harmon family — trusted in health & wellness for over 50 years.

How it works

How vaginal estriol helps

Falling estrogen can thin and dry vaginal tissue. Applied locally, low-dose estriol helps restore comfort right where symptoms occur, with minimal systemic exposure.

Targeted comfort

Relieves dryness, itching and irritation where you feel it.

Intimacy without discomfort

Helps restore tissue comfort for a better quality of life.

Milder, local estrogen

Estriol is a weaker estrogen, applied locally rather than throughout the body.

All-in, every month

One price covers everything

Provider care

Online visit, prescription & follow-ups with a licensed clinician.

Your medication

Prescribed and dispensed by a licensed U.S. pharmacy.

Free shipping

Delivered free and discreetly to your door.

Unlimited messaging

Reach your care team anytime with questions.

Estriol Vaginal Gel FAQ

Questions, answered

You'll see your exact price at checkout before you pay — one transparent price covers your online visit, your medication from a licensed U.S. pharmacy, and free, discreet shipping. No insurance or membership required.

Estriol is a milder, shorter-acting form of estrogen often used for local vaginal symptoms. Your provider will review whether it is appropriate for you.

Many people use local vaginal estrogen alongside systemic therapy. Your provider will review your full plan and confirm what is appropriate.

Care you can trust

Real physicians. Certified pharmacies.

Care from licensed U.S. physicians

  • Every plan is reviewed and prescribed by a U.S.-licensed physician — never a bot or an algorithm.
  • Your provider reviews your full medical history and prescribes only when treatment is appropriate for you.
  • The same care team stays with you — adjusting your dose and answering questions at every step.

Only 503A-certified pharmacies

We dispense only through U.S. state-licensed 503A compounding pharmacies — the highest-certified partners we work with, following USP compounding standards.

  • U.S. state-licensed 503A compounding pharmacies
  • Tested for purity and potency
  • Shipped free and discreetly to your door
90-day results guarantee

Results, or your money back.

Follow your provider's plan for 90 days. If you don't see progress, we'll refund your program — and you only ever pay if a provider prescribes treatment.

Start your journey → Only pay if you're prescribed

Refund covers the Harmon program fee for your first 90 days when the prescribed plan is followed; already-shipped compounded medication cannot be returned. Full terms provided at checkout.

Important safety information

Prescription hormone therapy requires an online consultation with a licensed provider who determines whether treatment is appropriate for you. Hormone therapy is not suitable for everyone and may carry risks and side effects; your provider will review your history, including any personal or family history of hormone-sensitive conditions. Compounded medications are not FDA-approved. This page is general information, not medical advice; individual results vary.

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