Photo is illustrative. Your medication’s packaging, form and appearance may differ depending on the prescribing pharmacy and your prescribed dose.
EstradiolRx
Physician-prescribed estradiol — the primary form of estrogen — to relieve hot flashes, night sweats, sleep disruption and other symptoms of perimenopause and menopause. Choose a daily oral tablet or a transdermal patch, prescribed by a licensed U.S. provider and delivered to your door.
- Eases hot flashes, night sweats and sleep disruption
- Oral tablet or transdermal patch — your provider helps you choose
- Physician-prescribed — no insurance required
No membership fee · same price at every dose
From the Harmon family — trusted in health & wellness for over 50 years.
How estradiol helps
As estrogen declines through perimenopause and menopause, symptoms like hot flashes and disrupted sleep set in. Estradiol restores estrogen to a level your provider tailors to you.
Symptom relief
Targets hot flashes, night sweats and mood and sleep changes.
Your rhythm back
Many people report steadier sleep and daytime energy within weeks.
Oral or patch
A daily tablet or a twice-weekly transdermal patch — your choice with your provider.
One price covers everything
Provider care
Online visit, prescription & follow-ups with a licensed clinician.
Your medication
Prescribed and dispensed by a licensed U.S. pharmacy.
Free shipping
Delivered free and discreetly to your door.
Unlimited messaging
Reach your care team anytime with questions.
Questions, answered
You'll see your exact price at checkout before you pay — one transparent price covers your online visit, your medication from a licensed U.S. pharmacy, and free, discreet shipping. No insurance or membership required.
Both deliver body-identical estradiol. The patch is applied twice a week and delivers estrogen through the skin; the tablet is taken daily. Your provider will help you choose based on your history and preferences.
If you still have your uterus, providers typically pair estrogen with progesterone to protect the uterine lining. Your provider will advise whether a combination is right for you — Harmon offers progesterone and a Bi-Est + Progesterone option as well.
Many people notice relief from hot flashes and night sweats within a few weeks, with fuller benefit over 2–3 months as your provider fine-tunes your dose.
More menopause & HRT care
Progesterone
Body-identical oral progesterone — often paired with estrogen to protect the uterine lining and support calm, restful sleep.
Menopause & HRT
See the full hormone-therapy lineup — estrogen, progesterone and combination options.
Real physicians. Certified pharmacies.
Care from licensed U.S. physicians
- Every plan is reviewed and prescribed by a U.S.-licensed physician — never a bot or an algorithm.
- Your provider reviews your full medical history and prescribes only when treatment is appropriate for you.
- The same care team stays with you — adjusting your dose and answering questions at every step.
Only 503A-certified pharmacies
We dispense only through U.S. state-licensed 503A compounding pharmacies — the highest-certified partners we work with, following USP compounding standards.
- U.S. state-licensed 503A compounding pharmacies
- Tested for purity and potency
- Shipped free and discreetly to your door
Results, or your money back.
Follow your provider's plan for 90 days. If you don't see progress, we'll refund your program — and you only ever pay if a provider prescribes treatment.
Refund covers the Harmon program fee for your first 90 days when the prescribed plan is followed; already-shipped compounded medication cannot be returned. Full terms provided at checkout.
Important safety information
Prescription hormone therapy requires an online consultation with a licensed provider who determines whether treatment is appropriate for you. Hormone therapy is not suitable for everyone and may carry risks and side effects; your provider will review your history, including any personal or family history of hormone-sensitive conditions. Compounded medications are not FDA-approved. This page is general information, not medical advice; individual results vary.