Photo is illustrative. Your medication’s packaging, form and appearance may differ depending on the prescribing pharmacy and your prescribed dose.
Estradiol Vaginal CreamRx
Physician-prescribed low-dose estradiol vaginal cream that treats symptoms locally — vaginal dryness, irritation, itching and discomfort with intimacy — with an optional Vitamin E formulation for added soothing. Prescribed by a licensed U.S. provider and delivered to your door.
- Relieves vaginal dryness, irritation and discomfort
- Applied locally — a low-dose, targeted approach
- Optional Vitamin E formulation for extra soothing
No membership fee · same price at every dose
From the Harmon family — trusted in health & wellness for over 50 years.
How vaginal estrogen helps
Falling estrogen can thin and dry vaginal tissue, causing irritation and discomfort. Applied locally, low-dose estradiol restores comfort right where symptoms occur.
Targeted comfort
Relieves dryness, itching and irritation where you feel it.
Intimacy without discomfort
Helps restore tissue comfort for a better quality of life.
Low, local dose
A targeted approach applied locally rather than throughout the body.
One price covers everything
Provider care
Online visit, prescription & follow-ups with a licensed clinician.
Your medication
Prescribed and dispensed by a licensed U.S. pharmacy.
Free shipping
Delivered free and discreetly to your door.
Unlimited messaging
Reach your care team anytime with questions.
Questions, answered
You'll see your exact price at checkout before you pay — one transparent price covers your online visit, your medication from a licensed U.S. pharmacy, and free, discreet shipping. No insurance or membership required.
Both deliver low-dose estradiol locally. The Vitamin E formulation adds Vitamin E for extra soothing. Your provider can help you choose.
Many people use local vaginal estrogen alongside systemic estrogen or combination therapy. Your provider will review your full plan and confirm what is appropriate.
More menopause & HRT care
Estradiol
Body-identical estradiol to ease hot flashes, night sweats and other menopause symptoms — as a daily tablet or a twice-weekly patch.
Menopause & HRT
See the full hormone-therapy lineup — estrogen, progesterone and combination options.
Real physicians. Certified pharmacies.
Care from licensed U.S. physicians
- Every plan is reviewed and prescribed by a U.S.-licensed physician — never a bot or an algorithm.
- Your provider reviews your full medical history and prescribes only when treatment is appropriate for you.
- The same care team stays with you — adjusting your dose and answering questions at every step.
Only 503A-certified pharmacies
We dispense only through U.S. state-licensed 503A compounding pharmacies — the highest-certified partners we work with, following USP compounding standards.
- U.S. state-licensed 503A compounding pharmacies
- Tested for purity and potency
- Shipped free and discreetly to your door
Results, or your money back.
Follow your provider's plan for 90 days. If you don't see progress, we'll refund your program — and you only ever pay if a provider prescribes treatment.
Refund covers the Harmon program fee for your first 90 days when the prescribed plan is followed; already-shipped compounded medication cannot be returned. Full terms provided at checkout.
Important safety information
Prescription hormone therapy requires an online consultation with a licensed provider who determines whether treatment is appropriate for you. Hormone therapy is not suitable for everyone and may carry risks and side effects; your provider will review your history, including any personal or family history of hormone-sensitive conditions. Compounded medications are not FDA-approved. This page is general information, not medical advice; individual results vary.